MDR Pseudomonas infections nearly twice as deadly for hospital patientsA review of hospital-onset Pseudomonas aeruginosa infections in the United States found that the mortality from multidrug-resistant P aeruginosa (MDR-PSA) is nearly twice that of non-MDR-PSA infections.For the study, which was presented at ASM Microbe 2017, which ended today, researchers used an electronic research dataset that includes microbiology/general lab results, pharmacy orders, and financial data to identify PSA isolates from blood, wound, urine, respiratory tract, gastrointestinal tract, and other sources collected at US hospitals from January 2013 to September 2015. Isolates were labeled as hospital-onset if they were collected more than 3 days after admission or through 1 day after discharge. The researchers then compared the mortality and hospital length of stay associated with MDR-PSA versus non-MDR-PSA infections.Of 4,522 cases, 3,643 (80.6%) were non-MDR and 879 (19.4%) were MDR-PSA. Isolates recovered from respiratory sources accounted for 42.4% of all MDR cases, followed by urine (33.1%), and wound (18.3%). While the overall mortality for all PSA infections was 12.8%, the researchers found that mortality was 19.8% for patients with MDR-PSA infections, compared with 11.1% for patients with non-MDR PSA infections. In addition, patients with MDR-PSA were in the hospital for 14.3 days longer than patients with non-MDR-PSA.Study co-author Sanjay Merchant, PhD, executive director of the Center for Observational and Real World Evidence at Merck & Co., told Infectious Disease News that the findings highlight the need for effective therapy against MDR PSA infections.”Additionally, hospitals should consider utilizing various infection management strategies, including hand hygiene, environment cleaning and increasing heterogeneity of antibiotic prescribing, to minimize the emergence and spread of MDR-PSA resistance in hospitals,” he said.Jun 3 ASM 2017 abstract (#5262, pg. 566) Jun 4 Infectious Disease News article Study evaluates alternative disinfectants for C difficileA new study by Dutch researchers in Antimicrobial Resistance & Infection Control indicates that Clostridium difficile spores of PCR ribotypes 014 and 027 strains are harder to eradicate than non-toxigenic PCR ribotype 010.The researchers were testing four different products commonly used for cleaning and disinfecting in Dutch hospitals for their efficacy against C difficile, the most common source of healthcare-associated diarrhea and a growing threat associated with morbidity, mortality, and extra costs. The four different compounds, potential alternatives to liquid bleach (the main disinfectant used against C difficile), included:Hydrogen peroxide 1.5%Glucoprotamin 1.5%A mixture of ethanol, propane, and N-alkyl amino propyl glycineA mixture of didecyldimonium chloride, benzalkonium chloride, polyaminopropyl, biguanide and dimenthicone as active ingredientsThe products, in wipe and spray form, were tested against ceramic tiles contaminated with an outbreak-related PCR ribotype (027), an endemic PCR ribotype (014), and a non-toxigenic ribotype (010). C difficile 014 is the most prevalent PCR ribotype in the Netherlands. The effectiveness was measured in reduction of colony-forming units (CFUs).Regardless of the disinfection method, the overall CFU reduction was highest for C difficile PCR 010, followed by 014 and 027. In general, the ready-to-use wipes performed better than the sprays for all compounds, with hydrogen peroxide wipes showing the highest bactericidal activity.”Ready-to-use wipes eliminate the possibility of human errors that could make the disinfectant less effective or make the wipes unnecessarily toxic,” the authors write.The authors say the findings indicate “the importance of including a variety of clinically relevant ribotypes when evaluating the effects of disinfectants against C difficile.”Jun 3 Antimicrob Resist Infect Control study
Last Updated: 13th May, 2020 08:46 IST Former National TT Champion Manmeet Singh Walia Dies Former national table tennis champion Manmeet Singh Walia, who was suffering from rare ALS disease for nearly two years, has died in Montreal, Canada WATCH US LIVE Press Trust Of India Former national table tennis champion Manmeet Singh Walia, who was suffering from rare ALS disease for nearly two years, has died in Montreal, Canada. Manmeet was 58 and is survived by his wife and two daughters. He succumbed to the disease on Monday. Manmeet was suffering from ALS (amyotrophic lateral sclerosis), a disease that causes motor neuron degeneration, leading to voluntary muscle impairment. Manmeet Singh Walia no moreHe had visited his doctors in Coimbatore also, trying to seek advice and find a cure. One of the finest and consistent performers in the ’80s, Manmeet became the national champion in 1989 when he beat S Sriram in the men’s singles final in Hyderabad. He had represented the country at multiple international events after making his debut at the Asian Championships in 1980 along with eight-time national champion Kamlesh Mehta.The Indian squad then, comprising Manjeet Singh Dua, Kamlesh Mehta, B. Arun Kumar, Manmeet and V. Chandrasekhar, led 4-2 before losing 4-5 to North Korea. Manmeet’s two crucial wins included beating then World number six Jo Young Ho, their top player, and another player who was World No. 13. Manmeet was all of just 18 then. Manmeet, however, could not repeat his Hyderabad performance in the subsequent nationals but he had made it to the finals four times on the trot since 1981. After he retired from the sport, he went to Canada and settled there. LIVE TV SUBSCRIBE TO US COMMENT His senior in the squad, Manjeet also spoke highly of his state-mate who could have gone on to play a few more years. “We thought his retirement was a little too premature,” he said. Kamlesh, too, echoed his views along a similar line. “In death, too, it was very early,” said Kamlesh, who was Manmeet’s teammate in Bank Sports Board tournaments. TTFI Secretary General M.P. Singh, condoling his death, said it was a sad moment for the entire table tennis fraternity. “I have interacted with him as a player during my playing days as well as in recent times when he came to Delhi a couple of years ago. I have lost a good friend,” he said. Image credits: PTI / Twitter Recalling his association with Manmeet, Kamlesh said that he was one of the best in the business those days. “He and I made our debut together in the Kolkata Asian championships. Only Chandra, Arun and Manmeet got to play the match against the North Koreans. And, Manmeet’s was crucial as he won both his rubbers and put India ahead. India finished fifth in the championships,” said Kamlesh. FOLLOW US First Published: 13th May, 2020 08:46 IST Written By
IMCA Sunoco Stock Car career wins number one and 100, and a lot of them in between, came at Shawano Speedway for Travis Van Straten. (Photo by A and H Photos)By Scott OwenSHAWANO, Wis. (July 29) – On July 14, 2001 IMCA Sunoco Stock Car rookie Travis Van Straten scored his first career feature win at Shawano Speedway.Sixteen years later, Van Straten – now one of the top IMCA Stock Car racers in the nation – scored his 100th feature win at the same venue. It was the 12th win of the season for the three-time defending track champion.Josh Mroczkowski led early on as Dan Michonski quickly moved to second after starting 10th. Michonski took the lead on lap five while Van Straten worked through the field and joined the top three by lap 10.Michonski, Van Straten, and Nolan went three-wide for the lead on lap 12 with Van Straten taking the top spot. Van Straten led the rest of the way for his historic 100th IMCA career feature win. Michonski finished second and Nolan was third.In other action, Marcus Yarie won his second local IMCA Modified feature of the season while Jordan Barkholtz won his fourth Karl Chevrolet Northern SportMod feature.